D vitamin forskningsresultat är ett hormon funktion

Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D

Kermpatsou, Despoina; Olsson, Frida; Wåhlén, Erik; Söderberg, Ola et al.

Ingår inom Journal of Steroid Biochemistry and Molecular Biology, 2024

A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Ingår inom natur Communications, 2022

Effects of 1a,25-dihydroxyvitamin D-3 and tacalcitol on fängelse signaling and anchorage-independent growth in T98G and U251 glioblastoma cells

Olsson, Frida; Sarri, Niki; Papadopoulos, Natalia; Lennartsson, Johan et al.

Ingår inom Biochemistry and Biophysics Reports, 2022

Effects of glucocorticoids on vitamin D₃-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts

Zayny, Ahmad; Almokhtar, Mokhtar; Wikvall, Kjell; Ljunggren, Östen et al.

Ingår inom Molecular and Cellular Endocrinology, 2019

Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: potential effects of vitamin D on brain steroidogenesis

Emanuelsson, Ida; Almokhtar, Mokhtar; Wikvall, Kjell; Gröndbladh, Alfhild et al.

Ingår inom Neurochemistry International, s.

46-55, 2018

Vitamin D Analogues Tacalcitol and Calcipotriol hämma Proliferation and Migration of T98G Human Glioblastoma Cells

Emanuelsson, Ida; Wikvall, Kjell; Friman, Tomas; Norlin, Maria

Ingår inom Neuroscience, 2018

Drug-mediated gene regulation of vitamin D₃ metabolism in primary human dermal fibroblasts

Norlin, Maria; Lundqvist, Johan; Ellfolk, Maria; Hellström Pigg, Maritta et al.

Ingår inom Basic & Clinical Pharmacology & Toxicology, s.

59-63, 2017

Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Almokhtar, Mokhtar; Wikvall, Kjell; Ubhayasekera, S. J. Kumari A.; Bergquist, Jonas et al.

Ingår inom Journal of Steroid Biochemistry and Molecular Biology, s. 178-188, 2016

Effects of osteoporosis-inducing drugs on vitamin D-related gene transcription and mineralization in MG-63 and Saos-2 cells

Wegler, Christine; Wikvall, Kjell; Norlin, Maria

Ingår inom Basic & Clinical Pharmacology & Toxicology, 2016

Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

Wicher, Grzegorz; Norlin, Maria

Ingår inom Journal of Steroid Biochemistry and Molecular Biology, s.

21-27, 2015

Protective effects of 27-and 24-hydroxycholesterol against staurosporine-induced fängelse death in undifferentiated neuroblastoma SH-SY5Y cells

Emanuelsson, Ida; Norlin, Maria

Ingår inom Neuroscience Letters, s. 44-48, 2012

Vitamin D-mediated regulation of CYP21A2 transcription – a novel mechanism for vitamin D action

Lundqvist, Johan; Wikvall, Kjell; Norlin, Maria

Ingår inom Biochimica et Biophysica Acta - General Subjects, s.

1553-1559, 2012

Effects of CYP7B1-related steroids on androgen receptor activation in different fängelse lines

Lundqvist, Johan; Norlin, Maria

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

973-979, 2012

1α,25-Dihydroxyvitamin D₃ exerts tissue-specific effects on estrogen and androgen metabolism

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s. 263-270, 2011

Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway

Norlin, Maria; Pettersson, Hanna; Tang, Wanjin; Wikvall, Kjell

Ingår inom Archives of Biochemistry and Biophysics, s.

236-241, 2011

Effects on DHEA levels bygd estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism

Svenningsen, ortnamn Fex; Wicher, Grzegorz; Lundqvist, Johan; Pettersson, Hanna et al.

Ingår inom Neurochemistry International, s. 620-624, 2011

1α,25-Dihydroxyvitamin D₃ affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells

Lundqvist, Johan; Norlin, Maria; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

1056-1062, 2010

Effects of CYP7B1-mediated catalysis on estrogen receptor activation.

Pettersson, Hanna; Lundqvist, Johan; Norlin, Maria

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s. 1090-1097, 2010

CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)

Norlin, Maria; Wikvall, Kjell

Ingår inom Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2010

Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells

Ellfolk, Maria; Norlin, Maria; Gyllensten, Katarina; Wikvall, Kjell

Ingår inom Molecular Pharmacology, s.

1392-1399, 2009

CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Pettersson, Hanna; Lundqvist, Johan; Oliw, Ernst; Norlin, Maria

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

1206-1215, 2009

CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1)

Norlin, Maria

Ingår inom Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2009

CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling

Pettersson, Hanna; Holmberg, Lisa; Axelson, Magnus; Norlin, Maria

Ingår inom The FEBS Journal, s.

1778-1789, 2008

Metabolism of a novel side chain modified Delta 8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation bygd CYP27A1

Pettersson, Hanna; Norlin, Maria; Andersson, Ulla; Pikuleva, Irina et al.

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

383-390, 2008

Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel mål for PI3K/Akt and MAPK signalling

Tang, Wanjin; Pettersson, Hanna; Norlin, Maria

Ingår inom Journal of Steroid Biochemistry and Molecular Biology, s. 63-73, 2008

Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

718-723, 2008

Regulation of human CYP27A1 bygd estrogens and androgens in HepG2 and prostate cells

Tang, Wanjin; Norlin, Maria; Wikvall, Kjell

Ingår inom Archives of Biochemistry and Biophysics, s. 13-20, 2007

Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Hosseinpour, Fardin; Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s.

603-607, 2007

Flutamide metabolism in kvartet different species in vitro and identification of flutamide metabolites in human patient urine bygd high performance liquid chromatography/tandem mass spectrometry.

Tevell, Annica; Lennernäs, Hans; Jönsson, Mats; Norlin, Maria et al.

Ingår inom Drug Metab Dispos, s. 984-92, 2006

Regulation of steroid hydroxylase CYP7B1 bygd androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s.

540-546, 2006

Regulation of steroid hydroxylase CYP7B1 bygd androgens and estrogens in prostate cancer LNCaP cells

Tang, Wanjin; Norlin, Maria

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s.

540-546, 2006

Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues

Tang, Wanjin; Eggertsen, Gösta; Chiang, John Y.L.; Norlin, Maria

Ingår inom Journal of Steroid Biochemistry and Molecular Biology, s. 42-51, 2006

Isolation and properties of the CYP2D25 promoter: Transcriptional regulation bygd vitamin D3 metabolites

Ellfolk, Maria; Norlin, Maria; Wikvall, Kjell

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s.

568-572, 2006

Regulation of sterol 27-hydroxylase in human monocyte-derived macrophages: up-regulation bygd transforming growth factor beta1.

Hansson, Magnus; Wikvall, Kjell; Babiker, Amir

Ingår inom Biochim Biophys Acta, s. 44-51, 2005

Transcriptional regulation of human oxysterol 7alpha-hydroxylase bygd sterol response element binding protein

Norlin, Maria; Chiang, John Y.

L.

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s. 158-164, 2004

Hormonal regulation of the human sterol 27-hydroxylase gene CYP27A1.

Araya, Zufan; Tang, Wanjin; Wikvall, Kjell

Ingår inom Biochemical Journal, s. 529-534, 2003

Gene structure of pig sterol 12alpha-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21)

Lundell, Kerstin; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

86-96, 2003

On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation

Norlin, Maria; von Bahr, Sara; Björkhem, Ingemar; Wikvall, Kjell

Ingår inom Journal of Lipid Research, s.

1515-1522, 2003

25-Hydroxylation of vitamin D3 in primary cultures of pig hepatocytes:evidence for a role of both CYP2D25 and CYP27A1

Hosseinpour, Fardin; Ibranovic, Ines; Tang, Wanjin; Wikvall, Kjell

Ingår inom Biochemical and Biophysical Research Communications - BBRC, s. 877-883, 2003

Metabolism of 25-hydroxyvitamin D3 bygd microsomal and mitochondrial vitamin D3 25-hydroxylases (CYP2D25 and CYP27A1): a novel reaction bygd CYP27A1

Araya, Zufan; Hosseinpour, Fardin; Bodin, Karl; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta - Molecular and fängelse Biology of Lipids, s.

40-47, 2003

Hormonal regulation of the human sterol 27-hydroxylase gene (CYP27A1)

Zufan, Araya; Tang, Wanjin; Wikvall, Kjell

Ingår inom Biochemical Journal, s. 529-534, 2003

Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver: no coordinate regulation of CYP7A1 and CYP27A1.

Bjorkhem, I; Araya, Zufan; Rudling, M; Angelin, B et al.

Ingår inom Journal of Biological Chemistry, s.

26804-26807, 2002

Metabolism of 4 beta -hydroxycholesterol in humans

Bodin, Karl; Andersson, Ulla; Rystedt, Eva; Ellis, Eva et al.

Ingår inom Journal of Biological Chemistry, s. 31534-31540, 2002

The importance of residues in substrate recognition site 3 for the catalytic function of CYP2D25 (vitamin D 25-hydroxylase)

Hosseinpour, Fardin; Hidestrand, Mats; Ingelman-Sundberg, Magnus; Wikvall, Kjell

Ingår inom Biochem Biophys Res Commun, s.

1059, 2001

Cloning and expression of a pig liver taurochenodeoxycholic acid 6α-hydroxylase (CYP4A21): a novel member of the CYP4A subfamily

Lundell, Kerstin; Hansson, Ronnie; Wikvall, Kjell

Ingår inom Journal of Biological Chemistry, s. 9606-9612, 2001

24-Hydroxycholesterol fryst vatten a substrate for hepatic cholesterol 7 alpha-hydroxylase (CYP7A)

Norlin, Maria; Toll, Anders; Bjorkhem, Ingemar; Wikvall, Kjell

Ingår inom Journal of Lipid Research, s.

1629-1639, 2000

Porcine microsomal vitamin D-3 25-hydroxylase (CYP2D25): Catalytic properties, tissue transport, and comparison with human CYP2D6

Hosseinpour, Fardin; Wikvall, Kjell

Ingår inom Journal of Biological Chemistry, s. 34650-34655, 2000

Oxysterol 7 alpha-hydroxylase activity bygd cholesterol 7 alpha-hydroxylase (CYP7A)

Norlin, Maria; Andersson, Ulla; Björkhem, Ingemar; Wikvall, Kjell

Ingår inom Journal of Biological Chemistry, s.

34046-34053, 2000

Cytochrome P450 Enzymes in the Metabolism of Cholesterol and Cholesterol Derivatives

Norlin, Maria

2000

Gene structure of pig sterol 12α-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6α-hydroxylase (CYP4A21)

Lundell, Kerstin; Wikvall, Kjell

Ingår inom Biochimica et Biophysica Acta